drugset / Trial / NCT02675452

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

NCT02675452

Phase 1 Terminated 141 enrolled Amgen
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The main objectives are to evaluate the safety and tolerability of AMG 176 monotherapy in participants with relapsed or refractory multiple myeloma and participants with relapsed or refractory acute myeloid leukemia.

Timeline

Start
2016-06-13
Primary completion
2024-05-27
Completion
2024-05-27

Drugs

EvaluationDrugModalityDoseRoute
Subject TAPOTOCLAX Small molecule Intravenous
Background Azacitidine Other / unclassified
Background Itraconazole Small molecule