drugset
drugset / Trial / NCT02677545

Ticagrelor Versus Clopidogrel in Carotid Artery Stenting

NCT02677545 ↗

Phase 2 Completed 210 enrolled University Hospital, Basel, Switzerland
RandomizedParallel-groupOpen-labelTreatment

Summary

Patients with symptomatic or asymptomatic carotid stenosis in whom carotid artery stenting is planned are randomised between antiplatelet therapy with ticagrelor plus aspirin or clopidogrel plus aspirin and examined with brain MRI before and after stent treatment. The proportion of patients with new ischaemic lesions on MRI after treatment is compared between the two groups.

Timeline

Start
2016-12
Primary completion
2022-04-28
Completion
2022-04-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clopidogrel Small molecule 75 mg —
Subject Ticagrelor Small molecule 90 mg —
Background Aspirin Small molecule 75 mg —
Background Aspirin Small molecule 100 mg —

Indications

carotid stenosis