The Effect of Buffered Lidocaine Versus Nonbuffered Lidocaine on Pain Scores During Infiltration for Vulvar Biopsies

Summary

Objective: To compare pain scores on a visual analogue scale during infiltration of local anesthetic for vulvar biopsies between women who are treated with buffered versus non- buffered lidocaine Hypothesis: Patients treated with buffered lidocaine at the site of vulvar biopsy will have lower pain scores on a visual analogue scale during the biopsy. Study Design: Double blinded randomized controlled trial Population: Women undergoing vulvar biopsy at the Women's Primary Care Center and The Program In Women's Oncology Clinic of a non-infectious vulvar lesion.

Timeline

Start

2015-06

Primary completion

2018-04

Completion

2018-04

Publications

• Villavicencio JC, Kulkarni A, Luis C, Mendez H, Raker C, Cronin B, Robison K. Sensation of Pain Using Buffered Lidocaine for Infiltration Before Vulvar Biopsy: A Randomized Controlled Trial. Obstet Gynecol. 2020 Mar;135(3):609-614. doi: 10.1097/AOG.0000000000003710.

Drugs

Indications