Capsaicin + Diclofenac Gel in Acute Back Pain or Neck Pain

Phase 3 Completed 746 enrolled Boehringer Ingelheim

RandomizedParallel-groupDouble-blindTreatment

Summary

This randomised, controlled multi-centre parallel group trial will assess the efficacy and tolerability of a topical formulation gel of the combination of diclofenac and capsaicin in comparison to gels with diclofenac alone, capsaicin alone, and placebo for the treatment of acute back pain or neck pain

Timeline

Start: 2016-05-09
Primary completion: 2017-07-13
Completion: 2017-07-21

Publications

Predel HG, Ebel-Bitoun C, Peil B, Weiser TW, Lange R. Efficacy and Safety of Diclofenac + Capsaicin Gel in Patients with Acute Back/Neck Pain: A Multicenter Randomized Controlled Study. Pain Ther. 2020 Jun;9(1):279-296. doi: 10.1007/s40122-020-00161-9. Epub 2020 Mar 27.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Capsaicin	Small molecule	0.075 %	Topical
Subject	Diclofenac	Other / unclassified	2 %	Topical

Indications

No indication recorded.