Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia

Summary

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

Timeline

Start

2016-10

Primary completion

2020-03-10

Completion

2020-03-10

Publications

• Karunakaran KD, Kussman BD, Peng K, Becerra L, Labadie R, Bernier R, Berry D, Green S, Zurakowski D, Alexander ME, Borsook D. Brain-based measures of nociception during general anesthesia with remifentanil: A randomized controlled trial. PLoS Med. 2022 Apr 22;19(4):e1003965. doi: 10.1371/journal.pmed.1003965. eCollection 2022 Apr.

Drugs

Indications

No indication recorded.