drugset / Trial / NCT02706899

Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS

NCT02706899

Phase 1/2 Terminated 19 enrolled Seagen Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a phase 1/2 study to evaluate the combination of vadastuximab talirine (SGN-CD33A; 33A) and azacitidine in subjects with previously untreated International Prognostic Scoring System (IPSS) Intermediate-2 or high risk myelodysplastic syndrome (MDS).

Timeline

Start
2016-02
Primary completion
2017-11-06
Completion
2017-11-06

Drugs

EvaluationDrugModalityDoseRoute
Subject vadastuximab talirine Unknown Intravenous
Background Azacitidine Other / unclassified 75 mg/m2 Intravenous