Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine

Summary

Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the drug might be used with an effect equal to higher dosage not buffered. Clinical data are needed to confirm these anecdotal data. No data exist comparing buffered local anesthetics at lower drug concentrations to current dosages commonly used in dental and oral surgical procedures

Timeline

Start

2016-03

Primary completion

2017-08

Completion

2017-09

Drugs

Indications

No indication recorded.