Pharmacokinetic-Pharmacodynamic Relationship of Metformin in Healthy Volunteers

Summary

Two doses of metformin with 12 hour interval * low dose group (375/250 mg) * high dose group (1000/1000mg)

Timeline

Start

2014-05

Primary completion

2014-09

Completion

—

Publications

• Chung H, Oh J, Yoon SH, Yu KS, Cho JY, Chung JY. A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study. PLoS One. 2018 Jan 17;13(1):e0191258. doi: 10.1371/journal.pone.0191258. eCollection 2018.

Drugs

Indications

No indication recorded.