Transbucal Dexmedetomidine for Prevention of Sevoflurane Emergence Agitation in Pre-school Children

NCT02720705 ↗

Phase 2/3 Completed 90 enrolled Assiut University

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The aim of this study is to evaluate the efficacy of transbucal dexmedetomidine given in preschool children undergoing tonsillectomy operations in the prevention sevoflurane agitation.

Timeline

Start: 2016-05
Primary completion: 2018-10
Completion: 2018-11

Publications

Abdel-Ghaffar HS, Abdel-Wahab AH, Roushdy MM. [Oral trans-mucosal dexmedetomidine for controlling of emergence agitation in children undergoing tonsillectomy: a randomized controlled trial]. Braz J Anesthesiol. 2019 Sep-Oct;69(5):469-476. doi: 10.1016/j.bjan.2019.06.012. Epub 2019 Oct 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	0.5 ug/kg	Oral
Comparator	Dexmedetomidine	Other / unclassified	1 ug/kg	Oral

Indications

No indication recorded.