Tocolytic Therapy for Preterm Labor in Multiple Gestation

Phase 3 Unknown 140 enrolled Tel-Aviv Sourasky Medical Center

RandomizedParallel-groupOpen-labelTreatment

Summary

To compare the tocolytic efficacy oxytocin receptor antagonist (Atosiban) with that of calcium channel blockers (Nifedipine) among women with multiple gestation who present with threatened preterm labor.

Timeline

Start: 2016-03
Primary completion: 2018-03
Completion: 2018-03

Publications

Wilson A, Hodgetts-Morton VA, Marson EJ, Markland AD, Larkai E, Papadopoulou A, Coomarasamy A, Tobias A, Chou D, Oladapo OT, Price MJ, Morris K, Gallos ID. Tocolytics for delaying preterm birth: a network meta-analysis (0924). Cochrane Database Syst Rev. 2022 Aug 10;8(8):CD014978. doi: 10.1002/14651858.CD014978.pub2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atosiban	Other / unclassified	100 ug	Intravenous
Subject	Nifedipine	Other / unclassified	20 mg	Oral
Subject	Nifedipine	Other / unclassified	40 mg	Oral

Indications

No indication recorded.