drugset / Trial / NCT02730871

Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®

NCT02730871

Phase 4 Terminated 173 enrolled Alcon Research
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of Brinzolamide 1%/Brimonidine 0.2% (SIMBRINZA®) dosed twice daily (BID) when added to Travoprost 0.004%/Timolol 0.5% (DUOTRAV®) in subjects with open-angle glaucoma or ocular hypertension.

Timeline

Start
2016-06-24
Primary completion
2018-07-13
Completion
2018-07-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Brimonidine Small molecule 0.2 % Other
Subject Brinzolamide Small molecule 1 % Other
Background Timolol Other / unclassified 0.5 % Other
Background Travoprost Other / unclassified 0.004 % Other