drugset / Trial / NCT02737787

A Phase I Study of WT1 or NY-ESO-1 Vaccine and Nivolumab For Recurrent Ovarian Cancer

NCT02737787 ↗

Phase 1 Completed 11 enrolled Memorial Sloan Kettering Cancer Center
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to test the safety of a combination of an investigational WT1 vaccine and another drug called nivolumab. This is the first time that the WT1 vaccine and nivolumab are being used in combination. Also, to test the safety of a combination of an investigational NY-ESO-1 vaccine and another drug called nivolumab.

Timeline

Start
2016-04
Primary completion
2023-04-06
Completion
2023-04-06

Drugs

EvaluationDrugModalityDoseRoute
Subject NY-ESO-1 Vaccine Vaccine 1 ml —
Subject Nivolumab Monoclonal antibody — Intravenous
Subject WT1 Vaccine Vaccine — —