Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants

Summary

In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total duration of 19 hours. Cerebral oxygenation, cardiac output, arterial oxygenation and heart rate will be measured continuously. Primary outcome is time with arterial oxygen saturation \< 80%.

Timeline

Start

2015-05

Primary completion

2017-04

Completion

2017-09

Drugs

Indications