drugset / Trial / NCT02745912

Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants

NCT02745912

Phase 1 Completed 30 enrolled Orexigen Therapeutics, Inc
NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to determine the effect of multiple oral doses of naltrexone/bupropion on the pharmacokinetics (PK) of a single oral dose of metformin.

Timeline

Start
2016-04
Primary completion
2016-06
Completion
2016-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupropion Small molecule 180 mg Oral
Subject Metformin Small molecule 850 mg Oral
Subject Naltrexone Small molecule 16 mg Oral

Indications

No indication recorded.