drugset / Trial / NCT02750943

Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease

NCT02750943

Completed 253 enrolled GlaxoSmithKline
RandomizedParallel-groupSingle-blindTreatment

Summary

This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis. This study will evaluate the efficacy of a dentifrice containing 0.454% weight by weight (w/w) stannous fluoride to control gingivitis and gingival bleeding following 12 weeks twice daily brushing, compared to a negative control dentifrice.

Timeline

Start
2015-11-01
Primary completion
2016-03-01
Completion
2016-03-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator sodium monofluorophosphate Unknown 1000 ppm Topical
Subject stannous fluoride Small molecule 0.454 % Topical

Indications