drugset / Trial / NCT02750943
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
RandomizedParallel-groupSingle-blindTreatment
Summary
This will be a single-center, 12 week, examiner-blind, randomized, stratified (gender and baseline mean whole mouth MGI score), two-treatment, parallel group, clinical study in healthy adult volunteers with moderate gingivitis. This study will evaluate the efficacy of a dentifrice containing 0.454% weight by weight (w/w) stannous fluoride to control gingivitis and gingival bleeding following 12 weeks twice daily brushing, compared to a negative control dentifrice.
Timeline
- Start
- 2015-11-01
- Primary completion
- 2016-03-01
- Completion
- 2016-03-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | sodium monofluorophosphate | Unknown | 1000 ppm | Topical |
| Subject | stannous fluoride | Small molecule | 0.454 % | Topical |