Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health

Summary

This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers. Changes in oral health related quality of life will be monitored using the Dentine Hypersensitivity Experience Questionnaire (DHEQ). The study will be conducted in participants in good general health, with pre-existing self-reported and clinically diagnosed tooth sensitivity at screening.

Timeline

Start

2016-05-23

Primary completion

2017-02-01

Completion

2017-02-03

Outcome

Mixed primary results

registry analysis (other test); Stannous Fluoride; p = 0.0944; Mean Difference (Final Values) 5.89 (95% CI -1.018 to 12.80); ANOVA NCT02752958 ↗

registry analysis (other test); Stannous Fluoride; p <0.0001; Mean Difference (Final Values) 16.99 (95% CI 10.128 to 23.849); ANOVA NCT02752958 ↗

Publications

• Mason S, Burnett GR, Patel N, Patil A, Maclure R. Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity. BMC Oral Health. 2019 Oct 22;19(1):226. doi: 10.1186/s12903-019-0919-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	stannous fluoride	Small molecule	0.454 %	Topical

Indications