drugset

drugset / Trial / NCT02755298

Chronic Clinical Effect of Acetazolamide

NCT02755298 ↗

Phase 2/3 Completed 24 enrolled University of Zurich

RandomizedCrossoverDouble-blindTreatment

Summary

The study seeks primarily to determine the chronic clinical effect of AZA on exercise capacity (6MWD) compared to placebo.

Timeline

Start: 2016-10
Primary completion: 2020-11
Completion: 2020-11

Publications

Lichtblau M, Saxer S, Muller J, Appenzeller P, Berlier C, Schneider SR, Mayer L, Furian M, Schwarz EI, Swenson ER, Bloch KE, Ulrich S. Effect of 5 weeks of oral acetazolamide on patients with pulmonary vascular disease: A randomized, double-blind, cross-over trial. Pulmonology. 2024 Jul-Aug;30(4):362-369. doi: 10.1016/j.pulmoe.2022.11.004. Epub 2023 Jan 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Acetazolamide	Small molecule	250 mg	Oral

Indications