drugset / Trial / NCT02767401
The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)
Phase 4
Completed
200 enrolled
The First Affiliated Hospital of Dalian Medical University
Beijing Anzhen Hospital · collabFirst Hospital of China Medical University · collabNanfang Hospital, Southern Medical University · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate the effect of percutaneous coronary intervention (PCI) on myocardial viability in coronary artery disease patients with single coronary total occlusion (CTO) lesions.
Timeline
- Start
- 2015-09-15
- Primary completion
- 2018-08-15
- Completion
- 2018-12-15
Publications
- Background Namazi M, Safi M, Vakili H, Saadat H, Alipour S, Mahjoob P, Taherkhani M, Pedari S, Taherion M, Rajabi Moghaddam H, Alhazifi A, Vatanparast M, Khaligh S. Evaluation of effective factors in success rate of intervention on CTO. Acta Med Iran. 2015;53(3):173-6.
- Background Stuijfzand WJ, Raijmakers PG, Driessen RS, van Royen N, Nap A, van Rossum AC, Knaapen P. Value of Hybrid Imaging with PET/CT to Guide Percutaneous Revascularization of Chronic Total Coronary Occlusion. Curr Cardiovasc Imaging Rep. 2015;8(7):26. doi: 10.1007/s12410-015-9340-2.
- Background Lee SH, Yang JH, Choi SH, Song YB, Hahn JY, Choi JH, Kim WS, Lee YT, Gwon HC. Long-Term Clinical Outcomes of Medical Therapy for Coronary Chronic Total Occlusions in Elderly Patients (>/=75 Years). Circ J. 2015;79(8):1780-6. doi: 10.1253/circj.CJ-15-0041. Epub 2015 May 28.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | — | — |
| Comparator | Atorvastatin | Small molecule | — | — |
| Comparator | Clopidogrel | Small molecule | — | — |
| Comparator | Metoprolol | Other / unclassified | — | — |
| Comparator | Rosuvastatin | Small molecule | — | — |
| Comparator | Ticagrelor | Small molecule | — | — |