drugset / Trial / NCT02767596
Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 Analog
NaSingle-groupOpen-labelTreatment
Summary
The study aims to examine the effectiveness of the short acting GLP-1 analog, Lixisenatide to achieve glycemic control in type 2 diabetes patients, in patients with failure of long acting GLP-1 analog. Patients who fail to achieve significant improvement in diabetes control on basal insulin and Liraglutide will be switched to basal insulin and lixisenatide treatment for 12 weeks. The primary outcomes will be changes in HBA1C and weight.
Timeline
- Start
- 2016-07-12
- Primary completion
- 2017-02
- Completion
- 2017-02-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lixisenatide | Peptide | 10 ug | Subcutaneous |
| Background | Degludec | Protein / enzyme biologic | — | — |
| Background | insulin detemir | Protein / enzyme biologic | — | — |
| Background | insulin glargine | Protein / enzyme biologic | — | — |