drugset / Trial / NCT02767596

Evaluation of Lixisenatide Efficacy in Diabetes Mellitus Type 2 With Failure of Other GLP-1 Analog

NCT02767596 ↗

Phase 4 Terminated 2 enrolled Laniado Hospital
NaSingle-groupOpen-labelTreatment

Summary

The study aims to examine the effectiveness of the short acting GLP-1 analog, Lixisenatide to achieve glycemic control in type 2 diabetes patients, in patients with failure of long acting GLP-1 analog. Patients who fail to achieve significant improvement in diabetes control on basal insulin and Liraglutide will be switched to basal insulin and lixisenatide treatment for 12 weeks. The primary outcomes will be changes in HBA1C and weight.

Timeline

Start
2016-07-12
Primary completion
2017-02
Completion
2017-02-21

Outcome

Outcome not reported

Stopped (Enrollment): “Insufficient recruitment rate”

Drugs

EvaluationDrugModalityDoseRoute
Subject Lixisenatide Peptide 10 ug Subcutaneous
Background Degludec Protein / enzyme biologic — —
Background insulin detemir Protein / enzyme biologic — —
Background insulin glargine Protein / enzyme biologic — —