Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.

Summary

The purpose of the study was to determine the effect of LCZ696 vs. enalapril on improvement of exercise capacity in patients with chronic heart failure with reduced ejection fraction.

Timeline

Start

2016-07-12

Primary completion

2019-11-25

Completion

2019-11-25

Outcome

Missed primary endpoint

registry analysis (superiority test); LCZ696 vs Enalapril; p = 0.2327; Least Squares (LS) Mean 0.32 (95% CI -0.21 to 0.85); ANCOVA NCT02768298 ↗

Drugs

Indications