drugset / Trial / NCT02768961
Program of Screening, Prevention and Elimination of Hepatitis C in Penitentiary Institutions in Cantabria (JAILFREE-C)
NaSingle-groupOpen-labelTreatment
Summary
The objectives of this study are: 1. To perform a systematic screening and evaluation of the prevalence of infection by hepatitis C virus (HCV), hepatitis B virus (HBV) and human immunodeficiency virus (HIV) in the prison population. 2. To perform an adequate characterization of patients and the characteristics of HCV infection in this population. 3. To evaluate the effectiveness and security in the prison population of an interferon-free antiviral regimen. 4. To evaluate the impact of a strategy of systematic HCV treatment on the rates of persistent infection, reinfection and super-infection in a prison population, in the short, medium and long term.
Timeline
- Start
- 2016-05-10
- Primary completion
- 2017-05-10
- Completion
- 2017-05-10
Publications
- Background European Association for Study of Liver. EASL Recommendations on Treatment of Hepatitis C 2015. J Hepatol. 2015 Jul;63(1):199-236. doi: 10.1016/j.jhep.2015.03.025. Epub 2015 Apr 21. No abstract available.
- Background Rice JP, Burnett D, Tsotsis H, Lindstrom MJ, Cornett DD, Voermans P, Sawyer J, Striker R, Lucey MR. Comparison of hepatitis C virus treatment between incarcerated and community patients. Hepatology. 2012 Oct;56(4):1252-60. doi: 10.1002/hep.25770.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ledipasvir | Small molecule | — | Oral |
| Subject | Sofosbuvir | Small molecule | — | Oral |