drugset / Trial / NCT02771418

The Effects of Anaesthesia on Cerebral Oxygenation and Cognitive Function in Carotid Endarterectomy

NCT02771418 ↗

Completed 40 enrolled Northern State Medical University
RandomizedParallel-groupSingle-blindSupportive care

Summary

Volatile anesthetics interfere with cerebral blood flow and reperfusion-ischemia injury via the mechanism known as a preconditioning. A transient deterioration of local hemodynamics and oxygenation during carotid endarterectomy (CEE) might involve both hemispheres of brain and affect postoperative cognitive function. The goal of this study was to assess the effects of anesthetics on perioperative cerebral oxygenation and cognitive functions.

Timeline

Start
2015-02
Primary completion
2016-06
Completion
2016-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule — Intravenous
Comparator Sevoflurane Other / unclassified — —