The Effects of Different Doses of Dexmedetomidine on Propofol Requirement for Loss of Consciousness Undergoing Bispectral Index: a Double-blinded, Placebo-controlled Trial

Completed 73 enrolled General Hospital of Ningxia Medical University

RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to evaluate the effects of different dexmedetomidine on the propofol requirement for loss of consciousness undergoing bispectral index.

Timeline

Start: 2016-06
Primary completion: 2016-08
Completion: 2016-08

Publications

Gu Y, Yang F, Zhang Y, Zheng J, Wang J, Li B, Ma T, Cui X, Lu K, Ma H. The effects of different doses of dexmedetomidine on the requirements for propofol for loss of consciousness in patients monitored via the bispectral index: a double-blind, placebo-controlled trial. BMC Anesthesiol. 2020 Apr 25;20(1):96. doi: 10.1186/s12871-020-01013-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	0.5 ug/kg	Intravenous
Comparator	Dexmedetomidine	Other / unclassified	1 ug/kg	Intravenous

Indications

No indication recorded.