drugset / Trial / NCT02818270

Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation

NCT02818270

NaSingle-groupOpen-labelHealth-services research

Summary

Aerosol delivery through a ventilator is influenced by numerous factors from ventilator-related, circuit-related to device-related factors. Aerosolized drug delivery through a ventilator system was studied on bench model with albuterol, yet the results were often overestimated. The objective of this study was to evaluate inhaled bronchodilator and mucolytic agents delivered through a ventilator system.

Timeline

Start
2016-06
Primary completion
2016-12
Completion
2016-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject N-acetylcysteine Small molecule Inhaled
Subject Salbutamol Unknown Inhaled