Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal

Summary

This study is designed to evaluate the addition of ketamine to dexmedetomidine as adjunctive therapies of severe alcohol withdrawal in medical ICU patients. Specifically, this study will assess whether the combination of ketamine and dexmedetomidine reduces the doses of conventional agents used for alcohol withdrawal while maintaining patient comfort and safety and will explore if the combination alters the expression of catecholamines in the serum over time.

Timeline

Start

2018-02

Primary completion

2018-12

Completion

2018-12

Outcome

Outcome not reported

Stopped (Business): “Funding not obtained”

Drugs

Indications