Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment

Summary

26 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration will be prospectively included. A single dose of ursodeoxycholic acid will be administered orally before surgery at different time-points in 22 subjects. Standard surgery will be performed and ocular samples will be collected during the procedure. Ursodeoxycholic acid treatment will be continued in treated patients during 3 months after surgery. Ocular and serum samples from the 4 untreated patients will serve as negative controls for the determination of UDCA levels.

Timeline

Start

2016-07

Primary completion

2017-09

Completion

2017-09

Drugs

Indications