drugset / Trial / NCT02848950

The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows

NCT02848950 ↗

Phase 2 Unknown 100 enrolled The Baruch Padeh Medical Center, Poriya
RandomizedParallel-groupOpen-labelTreatment

Summary

The basis for obesity's impact on reproduction is not well characterised and there is a controversy whether the key organ influenced by it are the ovaries or the uterus. Insulin sensitizers ameliorate insulin resistance in obese patients. This study seeks to determine if Metformin helps to increase fecundability by affecting the uterus in women undergoing ART. As a surrogate marker- flows in the uterus will be tested during the treatment.

Timeline

Start
2016-08
Primary completion
2017-06
Completion
2017-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule — Oral

Indications