drugset / Trial / NCT02850211

A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair

NCT02850211

Phase 4 Completed 180 enrolled Seoul National University Bundang Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Selective cyclooxygenase (COX)-2 inhibitors are commonly used analgesics that provide similar analgesia but reduced adverse effects compared to other analgesics. However, few studies have been conducted on postoperative pain and tendon-to-bone healing. Here, the investigators investigated the effect of a selective COX-2 inhibitor on analgesia and tendon-to-bone healing following arthroscopic rotator cuff repair.

Timeline

Start
2011-09
Primary completion
2015-11
Completion
2015-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Celecoxib Other / unclassified 200 mg Oral
Comparator Ibuprofen Small molecule 385 mg Oral
Comparator Tramadol Other / unclassified 50 mg Oral

Indications