drugset / Trial / NCT02852057

Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses

NCT02852057

Phase 1 Completed 2 enrolled University of Florida
NaSingle-groupOpen-labelTreatment

Summary

This study focuses on glaucoma therapy by drug eluting contact lenses. The contact lens will be loaded with timolol maleate and dorzolamide hydrochloride, both of which are commonly used ophthalmic drugs. Additionally, the lenses will contain vitamin E ((+) α-tocopherol) as an additive for achieving extended release of the drugs. This study is to assess the safety of the drug loaded contact lenses and the effectiveness. Effectiveness will be a drop in IOP after using the lenses.

Timeline

Start
2018-01-18
Primary completion
2021-08-10
Completion
2021-08-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dorzolamide Small molecule Other
Subject Timolol Other / unclassified Other

Indications