drugset / Trial / NCT02854631

Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)

NCT02854631

Phase 2 Completed 104 enrolled Gilead Sciences
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective of this study is to evaluate the safety and tolerability of selonsertib (GS-4997) in combination with prednisolone versus prednisolone alone in participants with severe alcoholic hepatitis (AH).

Timeline

Start
2016-09-01
Primary completion
2018-02-16
Completion
2018-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Selonsertib Small molecule 18 mg Oral
Background Prednisolone Other / unclassified 40 mg Oral

Indications