drugset / Trial / NCT02856126
HAIC Plus Sorafenib Versus TACE Plus Sorafenibfor Advanced HCC
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) compared with transarterial chemoembolization (TACE) in patients with BCLC stage hepatocellular carcinoma (HCC).
Timeline
- Start
- 2016-08
- Primary completion
- 2020-10
- Completion
- 2024-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | EADM | Unknown | — | Other |
| Subject | Leucovorin | Small molecule | — | Other |
| Comparator | Lobaplatin | Small molecule | — | Other |
| Comparator | MMC | Unknown | — | Other |
| Subject | Oxaliplatin | Small molecule | — | Other |
| Subject | fluorouracil | Small molecule | — | Other |
| Background | Sorafenib | Small molecule | 400 mg | Oral |