drugset / Trial / NCT02856698

MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)

NCT02856698 ↗

Phase 4 Terminated 111 enrolled Alberto Dominguez-Rodriguez
RandomizedParallel-groupOpen-labelTreatment

Summary

Acute pulmonary edema (APE) is a common condition in the emergency room, associated with considerable mortality. The use of intravenous morphine in the treatment of APE remains controversial and Benzodiazepines have been suggested as an alternative for morphine to relieving dyspnoea and anxiety in the patients with APE. The MIdazolan versus MOrphine in APE trial (MIMO) is a multicenter, prospective, open-label, randomized study designed to evaluate the efficacy and safety of morphine in patients with APE.

Timeline

Start
2017-04-08
Primary completion
2020-12-31
Completion
2020-12-31

Outcome

Outcome not reported

Stopped: “The study was stopped because of the adverse events”

Drugs

EvaluationDrugModalityDoseRoute
Subject Midazolam Small molecule 1 mg Intravenous
Comparator Morphine Other / unclassified 2 mg Intravenous
Comparator Morphine Other / unclassified 4 mg Intravenous

Indications