Pharmacodynamics Study of MRX34, MicroRNA Liposomal Injection in Melanoma Patients With Biopsy Accessible Lesions

Summary

This study is designed to investigate the biomarkers, pharmacodynamics and pharmacokinetics of the liposomal micro-ribonucleic acid-34 (microRNA-34, miR-34). Melanoma patients with easily accessible lesions will undergo serial biopsies and serial blood samples will be collected.

Timeline

Start

2016-08

Primary completion

2017-09

Completion

2017-12

Outcome

Outcome not reported

Stopped: “5 immune related serious adverse events in Phase 1 study”

Drugs

Indications