drugset / Trial / NCT02863120
Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is being done to evaluate the outcomes of patients undergoing total knee replacement with two different methods of local pain control:shots of liposomal bupivacaine, a long acting anesthetic, directly into the knee during surgery or anesthetic delivered continuously to the adductor canal to provide long term pain relief. The goal is to try to find a standard protocol that provides the greatest pain relief for patients undergoing total knee replacement.
Timeline
- Start
- 2016-07
- Primary completion
- 2019-12
- Completion
- 2019-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 15 ml | Other |
| Comparator | Bupivacaine | Other / unclassified | 20 ml | Other |
| Comparator | Bupivacaine | Other / unclassified | 30 ml | Other |
| Comparator | Ropivacaine | Other / unclassified | 550 ml | Other |