drugset / Trial / NCT02872090
Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)
RandomizedCrossoverQuadruple-blindTreatment
Summary
The aim of this interventional, randomized, double-blind, monocentric, cross-over study is to quantify the possible deleterious effect on the cardiac autonomic nervous system control of two long-acting anticholinergic bronchodilatators (tiotropium and glycopyrronium) and one beta-2 agonist long-acting bronchodilatator (indacaterol ) in patients with mild COPD.
Timeline
- Start
- 2016-03
- Primary completion
- 2021-06-01
- Completion
- 2021-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glycopyrronium | Unknown | — | Inhaled |
| Subject | Indacaterol | Other / unclassified | — | Inhaled |
| Subject | Tiotropium | Other / unclassified | — | Inhaled |