A Study to Evaluate the Safety and Tolerability of Valproic Acid in Trauma Patients(Part 2)

Summary

THIS IS THE SECOND PART OF A 2-PART STUDY. The purpose of the first part of this study was to determine the safety and tolerability of ascending doses of valproic acid (also known as Depacon) administered as intravenous infusion (IV) in doses ranging from 15 mg/kg to 250 mg/kg in healthy subjects. ID: VPA-C-002 The second part of the study will also be to determine the safety and tolerability of single ascending doses of valproic acid administered as IV in trauma subjects with hemorrhagic shock.

Timeline

Start

2016-11

Primary completion

2017-09-29

Completion

2017-09-29

Drugs

Indications