Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agents

Phase 4 Completed 53 enrolled Glaukos Corporation

NaSingle-groupOpen-labelTreatment

Summary

The study objective was to evaluate the intraocular pressure (IOP) lowering effect of two iStent devices in eyes of subjects with primary open-angle glaucoma, washed out of two anti-glaucoma medications (one a Prostaglandin) prior to stent implantation.

Timeline

Start: 2013-03
Primary completion: 2019-11-08
Completion: 2019-11-08

Publications

Background Berdahl J, Voskanyan L, Myers JS, Hornbeak DM, Giamporcaro JE, Katz LJ, Samuelson TW. Implantation of two second-generation trabecular micro-bypass stents and topical travoprost in open-angle glaucoma not controlled on two preoperative medications: 18-month follow-up. Clin Exp Ophthalmol. 2017 Nov;45(8):797-802. doi: 10.1111/ceo.12958. Epub 2017 Jun 2.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	Dexamethasone	Small molecule	0.1 %	Topical
Background	Tobramycin	Small molecule	—	Topical
Background	Travoprost	Other / unclassified	0.004 %	Topical

Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agents

Summary

Timeline

Publications

Drugs

Indications