drugset / Trial / NCT02880787

Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®

NCT02880787

Unknown 142 enrolled Central Hospital, Nancy, France
Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

The purpose is to evaluate the reproducibility of neuromuscular monitoring data of recovery from neuromuscular blockade, obtained with TOFScan® and TOF-Watch SX®, in adult and pediatric population. Secondary purposes are to evaluate the reproducibility of data obtained with 2 monitors for: * the onset of clinical action of curare: suppression of the first response of train of four monitoring (T1) of 95% initial value * the duration of clinical action of curare: recovery of the first response of train of four monitoring (T1) to 25% initial value * recovery of first (T1), second (T2), third (T3) and fourth response (T4) of train of four monitoring, and recovery of T4/T1 to 40% and 60% initial value (T4/T1 0.4 and 0.6) * complete recovery from curarisation, at T4/T1=90% and T4/T1=100%.

Timeline

Start
2014-11
Primary completion
2016-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Background Rocuronium Other / unclassified 0.6 mg/kg