drugset / Trial / NCT02888327
A Drug-Drug Interaction Study to Evaluate the Effect of AL-794 on the Pharmacokinetics of Oseltamivir and JNJ-63623872
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This open-label, four group, fixed-sequence study will evaluate the safety and pharmacokinetic interaction of AL-794 on oseltamivir, JNJ-63623872 (formerly VX-787) and probes for P-glycoprotein, CYP3A and OATP1B1 in healthy volunteers.
Timeline
- Start
- 2016-07-31
- Primary completion
- 2017-05-30
- Completion
- 2017-05-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AL-794 | Unknown | — | — |
| Subject | Digoxin | Other / unclassified | — | — |
| Subject | Midazolam | Small molecule | — | — |
| Subject | Oseltamivir | Small molecule | — | — |
| Subject | Pimodivir | Small molecule | — | — |
| Subject | Pitavastatin | Small molecule | — | — |