drugset / Trial / NCT02889692
Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma
Phase 3
Completed
23 enrolled
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital · collabShanghai Pulmonary Hospital, Shanghai, China · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators performed a randomized, double blind controlled, prospective study method on observation of Traditional Chinese Medicine (TCM) combined with targeted therapy maintenance to prolong the efficacy of long-term survival of advanced pulmonary adenocarcinoma patients. The investigators plan to involve 200 cases for observation in 3 years (100 cases for targeted therapy maintenance, 100 cases for targeted therapy maintenance plus TCM,), expecting that integrated TCM combined with targeted maintenance therapy has a better efficacy on prolonging progression-free survival time, overall survival, improving quality of life(QOL) of patients than that of targeted maintenance therapy.
Timeline
- Start
- 2013-03
- Primary completion
- 2016-12-30
- Completion
- 2017-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | YangYinFang | Unknown | 4 unknown | Oral |
| Subject | YiQiFang | Unknown | 4 unknown | Oral |
| Subject | YiQiYangYinFang | Unknown | 4 unknown | Oral |
| Background | Erlotinib | Small molecule | 150 mg | Oral |
| Background | Gefitinib | Small molecule | 250 mg | Oral |
| Background | Icotinib | Small molecule | 125 mg | Oral |