drugset / Trial / NCT02899078

Ibrutinib and Nivolumab in Treating Patients With Previously-Treated Metastatic Kidney Cancer

NCT02899078

NaSingle-groupOpen-labelTreatment

Summary

This phase Ib/II trial studies how well ibrutinib and nivolumab work in treating patients with previously-treated kidney cancer that has spread to other parts of the body. Ibrutinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Giving Ibrutinib and nivolumab may work better in treating patients with metastatic kidney cancer.

Timeline

Start
2016-11-15
Primary completion
2020-08-05
Completion
2021-02-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibrutinib Small molecule Oral
Subject Nivolumab Monoclonal antibody Intravenous

Indications