drugset / Trial / NCT02900742
Clinical Study of Chinese Medicine Plus Chemotherapy Maintenance in Advanced Non Small Cell Lung Cancer
Phase 3
Completed
71 enrolled
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital · collabShanghai Pulmonary Hospital, Shanghai, China · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators performed a randomized, prospective study method on observation of Traditional Chinese Medicine(TCM) combined with chemotherapy maintenance to prolong the efficacy of long-term survival of advanced non small cell lung cancer(NSCLC) patients.The investigators plan to involve 100 cases for observation in 3 years (50 cases for chemotherapy maintenance, 50 cases for chemotherapy maintenance plus TCM), expecting that integrated TCM combined with chemotherapy maintenance has a better efficacy on prolonging progression-free survival time, overall survival, improving quality of life(QOL) of patients than that of chemotherapy maintenance.
Timeline
- Start
- 2013-03
- Primary completion
- 2016-12-30
- Completion
- 2017-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | YangYinFang | Unknown | — | Oral |
| Subject | YiQiFang | Unknown | — | Oral |
| Subject | YiQiYangYinFang | Unknown | — | Oral |
| Background | Docetaxel | Small molecule | 75 mg/m2 | Intravenous |
| Background | Gemcitabine | Small molecule | 1250 mg/m2 | Intravenous |
| Background | Pemetrexed | Small molecule | 500 mg/m2 | Intravenous |