drugset / Trial / NCT02911285
NAC for Treating Comorbid PTSD and SUD
Phase 2
Completed
90 enrolled
Medical University of South Carolina
Institute for Translational Neuroscience · collabUnited States Department of Defense · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
As a result of sustained operations in Afghanistan and Iraq, there are an increasing number of U.S. military Veterans with substance use disorders and comorbid posttraumatic stress disorder (PTSD). If left untreated, individuals with substance use disorders and PTSD are at increased risk for developing other mental health problems (e.g., depression, anxiety), suicidal ideation and attempts, medical problems, reduced resiliency and military readiness, vocational problems, and family/social impairment. This study will determine the benefits of N-acetylcysteine (NAC) in treating alcohol use disorder and comorbid post-traumatic stress disorder (PTSD) among military Veterans.
Timeline
- Start
- 2016-10
- Primary completion
- 2019-08-05
- Completion
- 2019-11-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | N-acetylcysteine | Small molecule | 1200 mg | — |