drugset / Trial / NCT02917629

ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment

NCT02917629

Phase 2 Terminated 6 enrolled National Cancer Institute (NCI)
RandomizedParallel-groupDouble-blindPrevention

Summary

This randomized phase IIb trial studies how well ACTOplus met extended release (XR) works in treating in patients with stage I-IV oral cavity or oropharynx cancer that are undergoing definitive treatment. Chemoprevention is the use of drugs to keep oral cavity or oropharynx cancer from forming or coming back. The use of ACTOplus met XR may slow disease progression in patients with oral cavity or oropharynx cancer.

Timeline

Start
2018-05-31
Primary completion
2019-08-28
Completion
2019-08-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformide Unknown Oral
Subject Pioglitazone Small molecule Oral