drugset / Trial / NCT02924285

Catheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structural Heart Disease

NCT02924285

RandomizedParallel-groupOpen-labelTreatment

Summary

For therapy of symptomatic premature ventricular complexes (PVCs) in subjects with structural heart disease the current European Guidelines for the management of patients with ventricular arrhythmias and the prevention of second cardiac death recommend catheter ablation as well as amiodarone with a class IIa indication. Due to the lack of randomized data this study investigates the comparison of catheter ablation and amiodarone for PVC treatment in patients with structural heart disease. Therefore, patients will be randomized to one of two treatment strategies: 1) catheter ablation, or 2) amiodarone.

Timeline

Start
2017-11-01
Primary completion
2020-12-30
Completion
2021-03-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amiodarone Small molecule