drugset / Trial / NCT02924285
Catheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structural Heart Disease
Phase 3
Completed
80 enrolled
University of Leipzig
Abbott Medical Devices · collabHelios Health Institute GmbH · collabZentrum für Klinische Studien Leipzig · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
For therapy of symptomatic premature ventricular complexes (PVCs) in subjects with structural heart disease the current European Guidelines for the management of patients with ventricular arrhythmias and the prevention of second cardiac death recommend catheter ablation as well as amiodarone with a class IIa indication. Due to the lack of randomized data this study investigates the comparison of catheter ablation and amiodarone for PVC treatment in patients with structural heart disease. Therefore, patients will be randomized to one of two treatment strategies: 1) catheter ablation, or 2) amiodarone.
Timeline
- Start
- 2017-11-01
- Primary completion
- 2020-12-30
- Completion
- 2021-03-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amiodarone | Small molecule | — | — |