TAP Block With Magnesium Sulfate Added to Local Anesthetic in Abdominal Hysterectomy

Phase 2/3 Unknown 60 enrolled Assiut University

RandomizedCrossoverTriple-blindTreatment

Summary

Major abdominal surgeries are associated with severe abdominal pain, which can affect respiratory and cardiac functions, if insufficiently managed. This increases the incidence of post-operative morbidity. The objective of this study was to detect the efficacy and safety of magnesium sulphate as an adjuvant to the analgesia offered by local anesthetic in ultrasound guided TAP block in patients undergoing total abdominal hysterectomy.

Timeline

Start: 2016-01
Primary completion: 2016-06
Completion: 2016-11

Publications

Abd-Elsalam KA, Fares KM, Mohamed MA, Mohamed MF, El-Rahman AMA, Tohamy MM. Efficacy of Magnesium Sulfate Added to Local Anesthetic in a Transversus Abdominis Plane Block for Analgesia Following Total Abdominal Hysterectomy: A Randomized Trial. Pain Physician. 2017 Nov;20(7):641-647.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Magnesium Sulfate	Other / unclassified	200 mg	Other
Comparator	Bupivacaine	Other / unclassified	20 ml	Other

Indications

No indication recorded.