drugset / Trial / NCT02931253

Metformin as an Upstream Therapy in Atrial Fibrillation

NCT02931253 ↗

Phase 2 Terminated 6 enrolled The Guthrie Clinic
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to see if the study drug metformin will help patients who are overweight and have atrial fibrillation. This study aims to see if metformin helps patients stay in normal sinus rhythm after a catheter ablation. Metformin is investigational for use in patients with atrial fibrillation. Metformin is approved by the Food and Drug Administration (FDA) for use in patients with type 2 Diabetes Mellitus. Metformin is used with a proper diet and exercise program to control high blood sugar, and has been shown to help people lose weight. This study aims to look at the effects of metformin on weight loss and heart rhythm in patients with atrial fibrillation.

Timeline

Start
2017-04-11
Primary completion
2018-07-10
Completion
2018-07-10

Outcome

Outcome not reported

Stopped (Enrollment): “Recruitment issue: Enrollment expectation not met”

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 1000 mg Oral

Indications