Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children

Phase 1/2 Completed 90 enrolled Assiut University

RandomizedParallel-groupDouble-blindTreatment

Summary

Evaluate the efficacy of nebulized dexmedetomidine, nebulized ketamine, and nebulized midazolam a premedication prior to general anesthesia (GA) in oncologic preschool children undergo bone marrow aspirate and biopsy.

Timeline

Start: 2016-10
Primary completion: 2017-09
Completion: 2017-10

Publications

Abdel-Ghaffar HS, Kamal SM, El Sherif FA, Mohamed SA. Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy. Br J Anaesth. 2018 Aug;121(2):445-452. doi: 10.1016/j.bja.2018.03.039. Epub 2018 Jun 22.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	2 ug/kg	Other
Comparator	Ketamine	Small molecule	2 mg/kg	Other
Comparator	Midazolam	Small molecule	0.2 mg/kg	Other

Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children

Summary

Timeline

Publications

Drugs

Indications