drugset / Trial / NCT02942602
Effect of Lipid Modifying Drugs on HDL Function in Patients With Hyperlipidemia
RandomizedParallel-groupOpen-labelBasic science
Summary
1\) to test HDL function comprehensively in healthy and diseased individuals; 2) to evaluate if this test correlates with cardiovascular risk, independent of traditional risk factors; 3) and to differentiate effects of lipid-modifying or antiatherosclerotic drugs on HDL function and composition
Timeline
- Start
- 2014-04-03
- Primary completion
- 2016-05-23
- Completion
- 2016-05-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atorvastatin | Small molecule | 5 mg | — |
| Subject | Atorvastatin | Small molecule | 20 mg | — |
| Subject | Cholestyramine | Other / unclassified | 8 g | — |
| Subject | Ezetimibe | Unknown | 10 mg | — |
| Subject | Omega-3 fatty acids | Unknown | 2 g | — |