drugset / Trial / NCT02947386

Nimotuzumab and Nivolumab in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT02947386

Phase 1 Completed 7 enrolled Roswell Park Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the best dose and side effects of nimotuzumab when giving together with nivolumab and to see how well they work in treating patients with non-small cell lung cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Monoclonal antibodies, such as nimotuzumab and nivolumab, may block tumor growth in different ways by targeting certain cells.

Timeline

Start
2017-06-29
Primary completion
2021-04-15
Completion
2022-09-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Nimotuzumab Monoclonal antibody Intravenous
Subject Nivolumab Monoclonal antibody Intravenous